FDA Approved Oral Steroid #JATENZO

Know the dos &  dont’s related to Jatenzo
Nowadays, the craze for the muscular body has boomed drastically. People are consuming
Performance Enhancing Drugs (PEDs) for the same purpose, and even the people engaged in
competitive bodybuilding and sports. One of the drugs that have come into the limelight for
increasing muscle mass is known as Jatenzo. If you are here to know more about it, then you are
at the right place. Let's discuss everything about this drug in-depth.

What is Jatenzo?
It is an androgen approved by the Food and Drug Administrative (FDA) for use in males to treat
testosterone deficiency. It plays a vital role in maintaining sexual & reproductive features
(males), muscle mass, bone density, etc. Sometimes, medical conditions like dysfunction or
tumour of the pituitary gland, metabolic disorders, renal disorders, Kallman syndrome,
Klinefelter syndrome, estrogen excess, etc., can lower down testosterone levels. The condition in
which the testosterone level is lower than the normal range is called male hypogonadism.
Jatenzo is formulated with the active drug testosterone undecanoate (schedule iii controlled
substance) and recommended for testosterone replacement therapy. The government of different
countries have pre-determined rules and regulations on the usage of this drug.
When to use it?
As we discussed that this drug could help in boosting testosterone levels, there are some specific
cases or symptoms when it is recommended. These are:
 Primary hypogonadism, including congenital or acquired
Indications: Testicular failure due to cryptorchidism, bilateral torsion, chemotherapy, orchitis,
vanishing testis syndrome, orchiectomy, Klinefelter syndrome, or toxic damage from alcohol or
heavy metals
 Hypogonadotropic hypogonadism including congenital or acquired
Indications: Deficiency of Gonadotropin or luteinizing hormone-releasing hormone (LHRH) or
pituitary-hypothalamic injury from tumours, trauma, or radiation.
Limitations
Safety standards for this medication are not formulated for males below the age of 18 years.

When shouldn't Jatenzo be consumed?
 Men who are diagnosed (or suspected) with carcinoma of the breast or prostate
 Women, especially pregnant women and lactating mothers       
 People allergic to this compound
 Men with hypogonadal conditions which are not related to structural or genetic etiologies

Precautions
 Increase in blood pressure
If the BP hikes during the consumption of Jatenzo, it can increase the risk of MACE. Hence the
cardiological condition should be diagnosed before consumption of this drug.

 Polycythemia
Sometimes, an increase in the hematocrit reflective is observed in RBC mass, increasing the risk
of thromboembolic events.
 Cardiovascular Risks
Some studies suggest that usage of Jatenzo can become a threat to cardiovascular health by
increasing the risk of MACE.
 Benign Prostatic Hyperplasia (BPH) and Potential Risk of Prostate Cancer
Patients suffering from BPH are recommended not to consume androgens because it can worsen
the case. Moreover, it can make the patients prone to prostate cancer.
 Venous Thromboembolism
Patients undergoing testosterone replacement drugs experience symptoms of venous
thromboembolism, including deep vein thrombosis (DVT) and pulmonary embolism (PE).
 Spermatogenesis
Androgens can suppress spermatogenesis, which can lead to negative results in semen
parameters.
 Hepatic Adverse Effects
Patients taking this androgen for a long period shows symptoms of hepatic dysfunction (like
jaundice).
 Edema
Androgens can lead to excessive sodium and water retention in the body, which can lead to many
health complications, including edema.
Side effects
 Development of Gynecomastia (who are suffering from hypogonadism)
 Sleep apnea
 A negative change in the serum lipid profile
 Increased risk of hypercalcemia
 Disruption in hormones which can lead to the risk of depression and suicidal ideation
 Frequent headache
 Increase in serum PSA concentration
Conclusion
It is clear this drug is useful for treating testosterone deficiency, but there are many health
complications that can develop after consuming it. So it is better to consume it under medical
supervision.

Disclaimer 

This content is only for education, and we don'tdon't promote any felonious commodity. Please,
please stay away from harmful commodities for the betterment of our Nation. Use any
pharmaceutical drug under the supervision of a registered medical practitioner.
Jai Hind. 

Src:
https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/206089s000lbl.pdf
https://www.medicalnewstoday.com/articles/drugs-jatenzo